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PEKAŘÍK, V. -- PESKOVA, M. -- DUBEN, J. -- REMEŠ, M. -- HEGER, Z. Direct fluorogenic detection of palladium and platinum organometallic complexes with proteins and nucleic acids in polyacrylamide gels. Scientific Reports. 2020. v. 10, no. 23 July, ISSN 2045-2322.

Original name:
Direct fluorogenic detection of palladium and platinum organometallic complexes with proteins and nucleic acids in polyacrylamide gels
Czech name:
Written by (author):
Mgr. Vladimír Pekařík, Ph.D.
Marie Peskova
Jakub Duben
RNDr. Marek Remeš, Ph.D.
Mgr. Zbyněk Heger, Ph.D.
Department:
Department of Chemistry and Biochemistry
Kind of publication:
article in a professional periodical
Periodical:
Scientific Reports
Nature of article:
paper
Volume no. (year):
10
Periodical number within the volume:
23 July
Year of publication: 2020
Starting page:
Up to page:
Number of pages:
10
Sub-specification:
článek je obsažen v databázi Web of Science
UT code by Web of Science:
EID code by Scopus:
Form of publication: printed version
Original language:
English
Description in original language:
Allyl- and propargyl ethers of umbelliferone are sensitive probes for palladium and platinum, including anticancer compounds cisplatin, carboplatin and oxaliplatin, and effective for direct visualization of protein and DNA complexes with organometallic compounds in polyacrylamide gels allowing easy detection of interactions with analyzed protein or nucleic acid. Both probes can be used for fast evaluation of Pd/Pt binding to nanocarriers relevant in drug targeted therapy or specific clinically relevant target macromolecules.
Description in English:
Description in Czech:
Year of submission:
2020
Year of transmission:
RIV identification number:
 
Entry made by: Mgr. Kamila Zoufalá
Last change:
08/04/2020 12:29 (Mgr. Kamila Zoufalá)

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Source specification:

Scientific Reports. London: ISSN 2045-2322.

Original name:
Scientific Reports
Czech name:
Written by (author):
Kind of publication:
magazine
ISSN:
2045-2322
Country of publisher:
United Kingdom of Great Britain and Northern Ireland
Place of publishing:
London
Publisher:
Nature publishing group
URL:
http://www.nature.com/srep/
Reviewed magazine:
no
Original language:
English
Description in original language:
Description in English:
Description in Czech:
 
Entry made by:
Last change: 11/09/2016 11:10 (Šárka Novotná)

Evaluation of publication:

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