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RAUDENSKÁ, M. -- GUMULEC, J. -- BALVAN, J. -- MASAŘÍK, M. Caveolin-1 in oncogenic metabolic symbiosis. International Journal of Cancer. 2020. v. 147, no. 7, p. 1793--1807. ISSN 0020-7136. URL: https://onlinelibrary.wiley.com/doi/full/10.1002/ijc.32987

Original name:
Caveolin-1 in oncogenic metabolic symbiosis
Czech name:
Written by (author):
Department:
Department of Chemistry and Biochemistry
Kind of publication:
article in a professional periodical
Periodical:
International Journal of Cancer
Nature of article:
paper
Volume no. (year): 147
Periodical number within the volume:
7
Year of publication:
2020
Starting page:
1793
Up to page:
1807
Number of pages:
15
Sub-specification:
článek je obsažen v databázi Web of Science
UT code by Web of Science:
EID code by Scopus:
Form of publication:
printed version
Original language: English
Description in original language:
Metabolic phenotypes of cancer cells are heterogeneous and flexible as a tumor mass is a hurriedly evolving system capable of constant adaptation to oxygen and nutrient availability. The exact type of cancer metabolism arises from the combined effects of factors intrinsic to the cancer cells and factors proposed by the tumor microenvironment. As a result, a condition termed oncogenic metabolic symbiosis in which components of the tumor microenvironment (TME) promote tumor growth often occurs. Understanding how oncogenic metabolic symbiosis emerges and evolves is crucial for perceiving tumorigenesis. The process by which tumor cells reprogram their TME involves many mechanisms, including changes in intercellular communication, alterations in metabolic phenotypes of TME cells, and rearrangement of the extracellular matrix. It is possible that one molecule with a pleiotropic effect such as Caveolin-1 may affect many of these pathways. Here, we discuss the significance of Caveolin-1 in establishing metabolic symbiosis in TME.
Description in English:
Description in Czech:
Year of submission:
2020
Year of transmission:
RIV identification number:
URL:
https://onlinelibrary.wiley.com/doi/full/10.1002/ijc.32987
 
Entry made by:
Markéta Hejčová, DiS.
Last change: 08/10/2020 10:14 (Mgr. Kamila Zoufalá)

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Source specification:

International Journal of Cancer. Hoboken: ISSN 0020-7136.

Original name:
International Journal of Cancer
Czech name:
Written by (author):
Kind of publication:
magazine
ISSN:
0020-7136
Country of publisher:
United States of America
Place of publishing:
Hoboken
Publisher:
John Wiley & Sons, Inc.
URL:
https://onlinelibrary.wiley.com/journal/10970215
Reviewed magazine:
no
Original language:
English
Description in original language:
Description in English:
Description in Czech:
 
Entry made by:
Last change:
05/13/2020 13:17 (Šárka Novotná)

Evaluation of publication:

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