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ZMRHAL, V. -- SLÁMA, P. Immunomodulation of Avian Dendritic Cells under the Induction of Prebiotics. Animals. 2020. v. 10, no. 4, ISSN 2076-2615. URL: https://www.mdpi.com/2076-2615/10/4/698

Original name:
Immunomodulation of Avian Dendritic Cells under the Induction of Prebiotics
Czech name:
Written by (author):
Department:
Department of Morphology, Physiology and Animal Genetics
Kind of publication:
article in a professional periodical
Periodical:
Animals
Nature of article:
paper
Volume no. (year):
10
Periodical number within the volume: 4
Year of publication: 2020
Starting page:
Up to page:
Number of pages:
17
Sub-specification:
článek je obsažen v databázi Web of Science
UT code by Web of Science:
EID code by Scopus:
Form of publication:
printed version
Original language:
English
Description in original language:
Although the immunomodulatory properties of prebiotics were demonstrated many years ago in poultry, not all mechanisms of action are yet clear. Dendritic cells (DCs) are the main antigen-presenting cells orchestrating the immune response in the chicken gastrointestinal tract, and they are the first line of defense in the immune response. Despite the crucial role of DCs in prebiotic immunomodulatory properties, information is lacking about interaction between prebiotics and DCs in an avian model. Mannan-oligosaccharides, β-glucans, fructooligosaccharides, and chitosan-oligosaccharides are the main groups of prebiotics having immunomodulatory properties. Because pathogen-associated molecular patterns on these prebiotics are recognized by many receptors of DCs, prebiotics can mimic activation of DCs by pathogens. Short-chain fatty acids are products of prebiotic fermentation by microbiota, and their anti-inflammatory properties have also been demonstrated in DCs. This review summarizes current knowledge about avian DCs in the gastrointestinal tract, and for the first-time, their role in the immunomodulatory properties of prebiotics within an avian model.
Description in English:
Description in Czech:
Year of submission:
2020
Year of transmission:
RIV identification number:
URL:
https://www.mdpi.com/2076-2615/10/4/698
 
Entry made by:
Markéta Hejčová, DiS.
Last change:
04/17/2020 15:02 (Markéta Hejčová, DiS.)

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Source specification:

Animals. Basel: ISSN 2076-2615.

Original name:
Animals
Czech name:
Written by (author):
Kind of publication:
magazine
ISSN:
2076-2615
Country of publisher:
Swiss Confederation
Place of publishing:
Basel
Publisher:
MDPI AG (Multidisciplinary Digital Publishing Institute-MDPI)
URL:
http://www.mdpi.com/about/announcements/761
Reviewed magazine:
no
Original language:
English
Description in original language:
Description in English:
Description in Czech:
 
Entry made by:
Ing. Klára Švecová
Last change: 11/08/2016 13:25 (Šárka Novotná)

Evaluation of publication:

1
2
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45
        
12
3
45
bad
 
good
        uninteresting
 
interesting
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Average score: -        Assessed: 0
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123
4
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12
3
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amateur
 
professional
        
theoretical
 
practical
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