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CHUTVIRASAKUL, B. -- NUCHTAVORN, N. -- MACKA, M. -- SUNTORNSUK, L. Distance-based paper device using polydiacetylene liposome as a chromogenic substance for rapid and in-field analysis of quaternary ammonium compounds. Analytical and Bioanalytical Chemistry. 2020. v. 412, no. 13, p. 3221--3230. ISSN 1618-2642. URL: https://link.springer.com/article/10.1007/s00216-020-02583-y

Original name:
Distance-based paper device using polydiacetylene liposome as a chromogenic substance for rapid and in-field analysis of quaternary ammonium compounds
Czech name:
Written by (author):
Boonta Chutvirasakul
Nantana Nuchtavorn
doc. RNDr. Miroslav Macka, Ph.D.
Leena Suntornsuk
Department:
Department of Chemistry and Biochemistry
Kind of publication: article in a professional periodical
Periodical:
Analytical and Bioanalytical Chemistry
Nature of article: paper
Volume no. (year):
412
Periodical number within the volume:
13
Year of publication: 2020
Starting page:
3221
Up to page:
3230
Number of pages:
10
Sub-specification:
článek je obsažen v databázi Web of Science
UT code by Web of Science:
EID code by Scopus:
Form of publication:
printed version
Original language: English
Description in original language: This work presents an affordable distance-based microfluidic paper-based device (mu PAD), using polydiacetylene (PDA) liposome as a chromogenic substance with a smartphone-based photo editor, for rapid and in-field analysis of quaternary ammonium compounds (QACs) (e.g., didecyldimethylammonium chloride (DDAC), benzyldimethyltetradecyl ammonium chloride (BAC), and cetylpyridinium chloride (CPC)). In-field analysis of these compounds is important to ensure their antimicrobial activity and user safety since they are widely utilized as disinfectants in households and hospitals. The mu PAD featured a thermometer-like shape consisting of a sample reservoir and a microchannel as the detection zone, which was pre-deposited with PDA liposome. The color change from blue to red appeared in the presence of QACs and the color bar lengths were proportional to the QAC concentrations. Reactions of QACs with the PDA required a specific pH range (from pH 4.0 to 10.0) and a readout time of 7 min. Analytical performance characteristics of the device were tested with DDAC, BAC, and CPC showing acceptable specificity, accuracy (96.1-109.4%), and precision (%RSDs <= 9.3%). Limits of detection and quantitation were in the ranges of 20 to 80 and 70 to 250 mu M, respectively. Feasibility of the newly developed device was demonstrated for in-field analysis of QACs in fumigation solution providing comparable results with those obtained from a colorimetric assay (P > 0.05). The proposed device shows potentials for further applications of other analytes since it offers speed, simplicity, and affordability for in-field analysis, especially in remote areas where expertise, resources, and infrastructures are limited.
Description in English:
Description in Czech:
Year of submission: 2020
Year of transmission:
RIV identification number:
URL:
https://link.springer.com/article/10.1007/s00216-020-02583-y
 
Entry made by:
Last change: 05/07/2020 10:47 (Markéta Hejčová, DiS.)

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Source specification:

Analytical and Bioanalytical Chemistry. ISSN 1618-2642.

Original name:
Analytical and Bioanalytical Chemistry
English name:
Czech name:
Written by (author):
Kind of publication: magazine
ISSN:
1618-2642
Country of publisher:
Federal Republic of Germany
Place of publishing:
Publisher:
Springer
URL:
Reviewed magazine:
no
Original language:
Description in original language:
Description in English:
Description in Czech:
 
Entry made by:
Lenka Baláková
Last change:
03/14/2012 20:37 (Ing. Aleš Kutín)

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