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VANĚČKOVÁ, T. -- BEZDĚKOVÁ, J. -- HAN, G. -- ADAM, V. -- VACULOVIČOVÁ, M. Application of molecularly imprinted polymers as artificial receptors for imaging. Acta Biomaterialia. 2020. v. 101, no. 1 January, p. 444--458. ISSN 1742-7061. URL: https://doi.org/10.1016/j.actbio.2019.11.007

Original name:
Application of molecularly imprinted polymers as artificial receptors for imaging
Czech name:
Written by (author):
Department:
Department of Chemistry and Biochemistry
Kind of publication:
article in a professional periodical
Periodical: Acta Biomaterialia
Nature of article: paper
Volume no. (year):
101
Periodical number within the volume:
1 January
Year of publication:
2020
Starting page:
444
Up to page:
458
Number of pages: 15
Sub-specification: článek je obsažen v databázi Web of Science
UT code by Web of Science:
EID code by Scopus:
Form of publication: printed version
Original language:
English
Description in original language:
Medical diagnostics aims at specific localization of molecular targets as well as detection of abnormalities associated with numerous diseases. Molecularly imprinted polymers (MIPs) represent an approach of creating a synthetic material exhibiting selective recognition properties toward the desired template. The fabricated target-specific MIPs are usually well reproducible, economically efficient, and stable under critical conditions as compared to routinely used biorecognition elements such as fluorescent proteins, antibodies, enzymes, or aptamers and can even be created to those targets for which no antibodies are available. In this review, we summarize the methods of polymer fabrication. Further, we provide key for selection of the core material with imaging function depending on the imaging modality used. Finally, MIP-based imaging applications are highlighted and presented in a comprehensive form from different aspects. Statement of significance: In this review, we summarize the methods of polymer fabrication. Key applications of Molecularly imprinted polymers (MIPs) in imaging are highlighted and discussed with regard to the selection of the core material for imaging as well as commonly used imaging targets. MIPs represent an approach of creating a synthetic material exhibiting selective recognition properties toward the desired template. The fabricated target-specific MIPs are usually well reproducible, economically efficient, and stable under critical conditions as compared to routinely used biorecognition elements, e.g., antibodies, fluorescent proteins, enzymes, or aptamers, and can even be created to those targets for which no antibodies are available.
Description in English:
Description in Czech:
Year of submission:
2020
Year of transmission:
RIV identification number:
URL: https://doi.org/10.1016/j.actbio.2019.11.007
 
Entry made by: Markéta Hejčová, DiS.
Last change:
12/11/2019 09:35 (Markéta Hejčová, DiS.)

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Source specification:

Acta Biomaterialia. Oxford: ISSN 1742-7061.

Original name: Acta Biomaterialia
Czech name:
Written by (author):
Kind of publication: magazine
ISSN:
1742-7061
Country of publisher:
United Kingdom of Great Britain and Northern Ireland
Place of publishing:
Oxford
Publisher:
Elsevier
URL:
https://www.sciencedirect.com/journal/acta-biomaterialia
Reviewed magazine:
no
Original language:
English
Description in original language:
Description in English:
Description in Czech:
 
Entry made by:
Markéta Hejčová, DiS.
Last change:
12/10/2019 12:56 (Šárka Novotná)

Evaluation of publication:

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