Course syllabus D-MG - Molecular Genetics (FH - 2020/2021 - post-graduate studies)


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Course code:
D-MG
Course title in Czech:
Molecular Genetics
Course title in English: Molecular Genetics
Semester:
2020/2021
Mode of completion and number of credits:
Exam (0 credits)
Mode of delivery and timetabled classes:
full-time, 0/0 (hours of lectures per week / hours of seminars per week)
part-time, 0/0 (lectures per period / seminars per period)
Level of course:
doctor
Course type: optional
Type of delivery:
usual, consulting
Mode of delivery for our mobility students abroad: -- item not defined --
Language of instruction:
Czech
Course supervisor: doc. Mgr. Miroslav Baránek, Ph.D.
Course supervising department: Mendeleum - Institute of Genetics and Plant Breeding (FH)
Faculty:
Teachers:
doc. Mgr. Miroslav Baránek, Ph.D. (supervisor)
Prerequisites: none
 
Timetable in this semester:
-- item not defined --
 
Aim of the course and learning outcomes:
The aim of the course is to explain the students the basic mechanisms of a replication, expression, control and variability of genetic information at the molecular level build on the knowledge of the General genetics. After the subject passing, the student should have a clear imagine about the molecular mechanisms of the inheritance.
 
Course content:
1.
Introduction (allowance 0/0)
 
a.
history of molecular genetics from the evidence that NK is trailor of genetic information to human genome secvenation
b.current trends:-omics

2.
Chemical structure and function of NK (allowance 0/0)
 
a.
structure and function of DNA
b.
the basic structure of the RNA, the RNA in the cell function

3.
The central dogma of molecular biology, 1. Part (allowance 0/0)
 
a.
DNA replication, the basic principle, differences in prokaryot and eukaryotes
b.Transcription in prokaryots
c.
Transcription in eukaryots ,the RNA editing

4.
The central dogma of molecular biology, 2. Part (allowance 0/0)
 
a.
the genetic code, the basic principle of translation
b.the basic structure of proteins and amino acids
c.
the structure of ribosomal RNA, ribosomes ,differences in prokaryots and eukaryots, structure and function of tRNA
d.
the whole traslation approach, cotranslational and posttranslational modifications of proteins

5.The molecular structure of the chromatin (allowance 0/0)
 
a.
the structure of the nukleosome, the basic role and structure of the histons
b.the structure of chromatin, the structural function of the nonhistonic proteins
c.the analysis of chromosomes

6.
Regulation of gene expression (allowance 0/0)
 
a.
the regulation of gene expression in the prokaryots, Jacob-Monod model
b.
the regulation of gene expression at the eukaryotes, basic levels of regulation and their importance
c.
the basic groups of transposones, and the principle of transposition, the genome variability, epigenetics

7.
the OMICS (allowance 0/0)
 
a.
the global access to analysis of gene expression, genomics,transcriptomics, proteomics, metabolomics,
b.
basic methods of the genome and transcriptom analyses
c.conclusion, current trends in research

Learning activities and teaching methods:
Type of teaching method
Daily attendance
Combined form
consultation28 h0 h
preparation for exam42 h
0 h
Total
70 h
0 h
 
Assessment methods:
oral examination in the presence of examinator and supervisor
 
Assessment criteria ratio:
Requirement type
Daily attendance
Combined form
Total
0 %
0 %
 
Recomended reading and other learning resources:
Basic:
SIMMONS, M. -- SNUSTAD, P. Genetika. Brno: Masarykova univerzita, 2009. 871 p. ISBN 978-80-210-4852-2.
ROSYPAL, S. Úvod do molekulární biologie, díl první, díl druhý. Brno: Stanislav Posypal, 1998. 600 p. ISBN 80-902562-0-1.
CLARK, D. Molecular biology. Amsterodam: Elsevier, 2005. 784 p. ISBN 0-12-175551-7.

Course listed in study plans for this semester:
-- item not defined --
 
Course listed in previous semesters:
2019/2020 - post-graduate studies, 2018/2019 - post-graduate studies, 2017/2018 - post-graduate studies, 2016/2017 - post-graduate studies, 2015/2016 - post-graduate studies, 2014/2015 - post-graduate studies (and older)
Teaching place:
Brno, Lednice


Last modification made by Josef Knézlík on 07/23/2020.

Type of output: