Sylabus předmětu MBG - Molecular and Cell Genetics (FA - WS 2019/2020)

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Course code: MBG
Course title in language of instruction: -- item not defined --
Course title in Czech: Molecular and Cell Genetics
Course title in English: Molecular and Cell Genetics
Mode of completion and number of credits: Exam (6 credits)
(1 ECTS credit = 28 hours of workload)
Mode of delivery/Timetabled classes: full-time, 2/2 (hours of lectures per week / hours of seminars per week)
Language of instruction: Czech
Level of course: bachelor; master; master continuing
Semester: WS 2019/2020
Name of lecturer: prof. RNDr. Aleš Knoll, Ph.D. (examiner, instructor, lecturer, supervisor)
Prerequisites: none
Aims of the course:
Introduction to basic genetic mechanisms on the molecular and cellular level. Gaining knowledge about the molecular basis of genetic variability and the possibilities of applications of this knowledge.
Course contents:
1.Cells and genomes (allowance 2/2)
2.Informational macromolecules (nucleic acids, proteins), structure of DNA a chromosomes (allowance 2/2)
3.Gene and genome structure in animals, genomics (allowance 2/2)
4.Basic genetic mechanisms - replication, transcription and a translation (allowance 2/2)
5.Regulation of expression of genetic information (allowance 2/2)
6.Mechanisms of DNA repair in cells, mutation and recombination (allowance 2/2)
7.Genetic polymorphism, genetic markers - types; single nucleotide polymorphisms (allowance 2/2)
8.Basic methods in molecular biology, recombinant DNA (allowance 2/2)
9.Application of molecular genetics in breeding (genome analysis, genome manipulation) (allowance 2/2)
10.Using markers, candidate genes, gene and QTL mapping, whole genome analysis, genomic selection (allowance 2/2)
11.Structural genomics (genome sequencing) a functional genomics (gene expression study); proteomics (allowance 2/0)
12.Current Topic - GMO animals and animal cloning (allowance 2/0)
13.Excursion to the laboratory of cell genetics (allowance 0/4)
14.Excursion to the laboratory of molecular genetics (allowance 2/6)
Learning outcomes and competences:
Generic competences:
-Ability to analyse and synthesize
-Ability to apply knowledge
-Ability to create new ideas (creativity)
-General knowledge
-Science and research skills
-Skilled at utilizing and processing information

Specific competences:
-Ability to apply knowledge of molecular genetics in animal breeding
-Knowledge of basic genetic mechanisms at the molecular and cellular level
-Knowledge of modern biotechnology in animals
-Knowledge of the mechanisms regulating the expression of genetic information

Type of course unit: required
Year of study: Not applicable - the subject could be chosen at anytime during the course of the programme.
Work placement: There is no compulsory work placement in the course unit.
Recommended study modules: -
Learning activities and study load (hours of study load):
Type of teaching methodDaily attendance
Direct teaching
     lecture26 h
     practice20 h
     professional educational excursion10 h
     preparation for exam60 h
     preparation for regular assessment20 h
     preparation for regular testing16 h
     writing of seminar paper16 h
Total168 h
Assessment methods:
Exam. The exam consists of a written and an oral part. The written part consists of 20 questions. The written examination is reserved for 45 minutes. Each question is evaluated by 2 points. At least 25 points are needed to progress to the oral part of the exam. At the oral part, the student responds to the two questions. Theoretical knowledge in accordance with the syllabus is required. They are also required knowledge of the exercises (problem solving). Students prepare and present a seminar paper.
Recommended reading:
TypeAuthorTitlePublished inPublisherYearISBN
RQALBERTS, B.Základy buněčné biologie : úvod do molekulární biologie buňkyÚstí nad LabemEspero Publishing200580-902906-2-0
REROSYPAL, S.Úvod do molekulární biologie80-902562-1-X
REROSYPAL, S.Úvod do molekulární biologie.BrnoS. Rosypal200580-902562-5-2
REMolecular biologyAmsterdamElsevier0-12-175551-7


Last modification made by Ing. Michal Karhánek on 11/20/2019.

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